Thursday, 15 March 2012

Nurses reach pact at County Hospital

After five months of negotiations, the nurses union at CookCounty Hospital reached a tentative agreement with management on anew short-term contract, officials said Thursday.

The agreement, hammered out with county officials lateWednesday, affects 1,200 registered nurses at County Hospital, 200 atOak Forest Hospital and 100 at County Jail hospital and the countyHealth Department.

Neither union nor county officials would comment on the terms ofthe agreement.

The nurses, members of the Illinois Nurses Association, areexpected to vote on the agreement next week. But the agreement, ifapproved, would be in place for only a short time because county andunion …

Emma Thompson writing new 'Peter Rabbit' book

NEW YORK (AP) — Academy Award-winning actress Emma Thompson is writing a new "Peter Rabbit" story.

The book is to be published by Penguin in September 2012.

Penguin announced Thursday the book will be called "The Further Tale of Peter Rabbit." The book will be set in Scotland, where Peter Rabbit creator Beatrix Potter …

Heat C Jermaine O'Neal misses game against Hawks

Heat center Jermaine O'Neal is out of the lineup against the Atlanta Hawks with a strained groin and hip flexor.

It's the fourth time O'Neal has missed a game this season, although two of those were to attend a family funeral. Joel Anthony started Monday night in place of …

Wednesday, 14 March 2012

Get cozy with TV holiday fare

What's new in the world of holiday television? As usual, notmuch. But we will get to see Kathie Lee Gifford and 'N Sync togetherat last, and fresh holiday adventures from the "Veggie Tales" and"All Dogs Go to Heaven" gangs. One old favorite - the show-stoppingHeat Miser from "The Year Without a Santa Claus" - returns to networkTV after an eternity in cable exile.

Here are holiday highlights from now through Christmas. Alltimes are Central.Today

"The Story of Santa Claus," 7 p.m., Channel 2: Animated musicalwith Edward Asner as St. Nick."The Nutcracker," 9 p.m., Bravo: The Tchaikovsky fairy taledanced by the Kirov Ballet.Friday, Dec. 11"Babes in Toyland," 6 …

Machining firm set to expand its arsenal

A Hanover-based machining company is gearing up for expansion, planning to add a state-of-theart laser to its shop floor, and building a new facility.

According to Fred Wilke, secretary treasurer of Wilke Enginuity Inc., the company is adding a new building on its property at 250 O'Brien Lane. The addition will double Wilke's on-site square footage.

The laser, used for precision cutting, will cost more than the new building.

Also possibly in the works is an antique tractor museum, he said.

Wilke Enginuity will add a fourth laser to its cutting arsenal. Although the company already has three lasers, the newest of them, 3 years old, is already considered obsolete …

D'Orazio leads Soul past SaberCats in ArenaBowl

Matt D'Orazio turned out to be one of the best insurance policies in Arena League history. Brought in as a backup quarterback before the season, he capped off an MVP season by leading the Philadelphia Soul to a championship.

D'Orazio threw seven touchdown passes and ran for another score as the Soul won its first ArenaBowl, beating defending champion San Jose 59-56 on Sunday.

Philadelphia scored on all six of its first-half possessions and took the lead for good with three consecutive touchdowns in the second quarter, then survived a frantic San Jose rally in the final minute to hold on in the 22nd ArenaBowl.

D'Orazio replaced injured starter Tony …

Let's Go: ; WHAT'S GOING ON AROUNG HERE

Play by students to portray East End history

An original play on East End history will be presented bystudents of Roosevelt Junior High School at 7 p.m. today at theCultural Center Theater. The 45-minute play is based on students'interviews with older residents who grew up in the East End.Photographs of the area and of downtown Charleston will be displayedat a reception to follow.

Sponsors are the East End Association and Roosevelt Junior HighSchool.

Symphony to premiere 'Suite Festiva'

Brazilian composer Ronaldo Miranda will be present when the WestVirginia Symphony offers the North American premiere of his work,"Suite Festiva," at 8 p.m. Saturday at …

October Suite

OCTOBER SUITE

By Maxine Clair

Random House, October 2001, $23.95

ISBN 0-375-50630-6

In October Suite, Maxine Clair reprises the character of October Brown, who we encountered in Clair's astonishing 1994 short story collection, Rattlebone, winner of the Chicago Tribune's Heartland Prize for Fiction and the American Library Association's Black Caucus Award for 1995. In Rattlebone, we see the feisty October Brown only obliquely -- through the eyes of school children wary of the splotch of white vitiligo on her chocolate-smooth cheek that they call her "devil's kiss." One child in particular, Irene Wilson, has reason to resent October.

Brown, the pretty …

Mothers for Peace take on nuclear waste storage

At the western edge of a largely dormant anti-nuke movement, three generations of mothers are tilting at nuclear reactors. But their mission is less quixotic than it might appear.

Wielding a novel argument about the potential impact of a terrorist attack on nuclear facilities, San Luis Obispo Mothers for Peace is aiming to set legal precedent requiring tougher environmental reviews for nuclear power plants and radioactive waste storage nationwide.

It's the latest chapter in a long-running battle that pits the all-volunteer group of aging hippies, activists and teachers against the federal government, Pacific Gas and Electric Co., and PG&E's Diablo Canyon …

Sox, Dotson come close // Whitt's double lifts Jays

BLUE JAYS 3WHITE SOX 2

Richard Dotson was one pitch from a tidy triumph for the WhiteSox Wednesday night. All he needed was a strike. One more strike.

He threw it, but Ernie Whitt hit the 0-and-2 pitch so hard thatby the time the dented ball was retrieved from the right-fieldcorner, two runs were in and Dotson was a 3-2 loser to the Blue Jays.

All for the lack of a double play. Two double plays.

"We had two chances and didn't make either one," manager JimFregosi said. "When you make errors in the ninth inning of a one-rungame, you're going to lose, and we did."

The Sox lost because Ozzie Guillen was too hasty in his attemptto take a throw …

Stocks Tumble; Dow Drops More Than 150

NEW YORK - Wall Street pulled back Wednesday, sending the Dow Jones industrials down more than 160 points on Merrill Lynch & Co.'s severe credit-related losses and a sharp September drop in existing home sales.

The market got one of its most-feared scenarios: Not only is the housing implosion dampening corporate profits, it's accelerating.

Merrill said it wrote down $7.9 billion in fixed-income instruments called collateralized debt obligations and from defaulting subprime mortgages - more than the $5 billion writedown the investment bank estimated earlier this month. The result was a net loss for the quarter of $2.3 billion.

The worse-than-anticipated loss …

Zimbabwean opposition supporters seek refuge at South African Embassy

South Africa says scores of Zimbabwean opposition supporters are seeking refuge from political violence at its embassy in Harare for a second day.

At midmorning Thursday, people could be seen sitting in the sun or sleeping in the embassy parking lot. At least one road block obstructed the street leading up to the embassy's main entrance, and riot police were on a …

3 Teens Charged in Gang Killing

Three teenagers who opened fire on rival gang members Fridaynight have been charged with murder after accidentally shooting a14-year-old member of their own gang, police said.

The dead youth was identified as Fredrick Alston of the 1000block of West 88th St.

Alston was acting as "point man" in an assault on rival gangmembers at the time of the 9:15 p.m. shooting in the 1300 block ofWest 87th.

Charged were Antuan Winsley, 18, of the 1300 block of West 89thSt., and two 15-year-old juveniles charged as adults - MichaelBoston, of 8800 block of South Ada, and Timothy Williams, of the 8700block of South Morgan.

The Sun-Times incorrectly reported Sunday that Simon Williams,17, of the 8700 block of South Justine, had been charged with theslaying.

Williams was charged with aggravated discharge of a firearm.

Tuesday, 13 March 2012

D'Amato Apologizes For Mocking Judge

NEW YORK Sen. Alfonse D'Amato (R-N.Y.) apologized Wednesday formocking O. J. Simpson trial Judge Lance Ito by talking in a phonyJapanese accent.

D'Amato's remarks, made Tuesday on a nationally syndicated radioprogram, infuriated Japanese Americans.

"If I offended anyone, I'm sorry," he said. "I was making funof the pomposity of the judge and the manner in which he's draggingthe trial out."

D'Amato launched into his imitation when he and radio host DonImus were discussing reopening Senate Banking Committee hearings onWhitewater.

Imus suggested that D'Amato, who is committee chairman, wouldn'tattract as large an audience as long as the Simpson trial is goingon. "Judge Ito will never let it end," D'Amato said in a fake accent."Judge Ito loves the limelight. He is making a disgrace of thejudicial system. Little Judge Ito. . . . Judge Ito will keep usfrom getting television for the next year."

Cyril Nishimoto, director of Manhattan-based Japanese AmericanSocial Services, denounced the remarks as "racist and completelyinsensitive."

Laura McPhee

BOSTON

Laura McPhee

MUSEUM OF FINE ARTS, BOSTON

In the photograph used on the museum handout fur Laura McPhee's recent exhibition, smoky rays of sunlight stream into dense forest as fire licks at the roots of trees in the center of the frame. In the foreground, more sunlight illuminates underbrush while branches to the upper right and left almost touch the lens, creating a path for the eye that seems to lead a hundred feet deep. The highly theatrical composition resembles nothing so much as a picture by Gregory Crewdson, and when one realizes that Understory Flareups, Fourth of July Creek, Valley Road Wildfire, Custer County, Idaho, 2005, is not staged, one has to wonder why it was treated so formally, so luxuriously, with such a sense of portent.

The wall text provides an answer-in format, technique, and subject matter, McPhee is referring to the nineteenth-century painters and photographers of the American landscape. McPhee's choice of large-format, unretouched prints nods to the (very) old school, and her presentation of them at such large scale references the work of Albert Bierstadt and friends. But neither tactic succeeds beyond simply helping make serviceable depictions of the obvious-that the West is full of contrasts-seem a few degrees more delicious. Despite her claims to a less romantic eye-she portrays, for example, a cyanide-evaporation pool at a mine, a settler's cabin from the 1920s just down the slope from a recent housing development designed to look like log cabins, and endangered salmon at a fish hatchery-her West is just as thoroughly aestheticized as that of her nineteenth-century referents.

Surprisingly, there is little relationship here to the recently much discussed American roadster photographers of the '70s, who were thefirst to use color in fine-art photography and to trace their roving landscaper impulses and taste for large-format plates to figures like William Henry Jackson. Little indicates that McPhee has learned from their example how to depict ugly America without too much attitude: Her inability to resist using a model-beautiful local girl, while an interestingly old-fashioned impulse, produces a very contemporary hint of Abercrombie and Fitch.) And rather than start from the baseline idea that all landscape is human, she sticks primarily to the depiction of binaries (old and new, rural and industrial, etc.).

Two pictures in the show highlighted, for opposite reasons, the problems presented by the rest. In Skinned EIk, White Cloud Mountains, Idaho, 2004, one of a trio of shots of a gutted elk bloodying a snowy forest clearing, a mess of boot prints in the picture's lower right generates a surprising sense of texture and human presence. Here, McPhee abandons her own standards of beauty to positive effect. In another. Igloo Built from Downloaded Plans, Park Creek, Custer County, Idaho, March, 1005, a small, lopsided igloo lit from the inside glows against a nocturnal landscape-a funny, found moment of outer space on earth that begs for, and receives, all the benefits of McPhee's technical and aesthetic skill. These two prints suggest that McPhee has ways and means of portraying the normal, the strange, and the vast territory in between without sealing them completely away from us under a perfect skin or overstating a quality of mystery that's already there.

-Larissa Harris

Paul Horn

HOUSTON

TEXAS GALLERY

For his solo debut exhibition, "Death Metal 2000: Prehistoria," Houston-based artist Paul Horn spray painted a child's plastic playhouse in gold, dusting its roof with powdery glitter to create an air of fantasy and wonder. Inside the structure, which sat on an island of Astroturf, a golden skeleton lay sprawled on the floor, and a stack of gilded skulls filled the sink. Plastic Snoopys, robots, and other action figures lined the interior walls, and surrounding the playhouse were assemblages built from Power Wheels, plastic cars big enough for kids to sit in and "drive." Elsewhere, cardboard boxes painted white served as pedestals for stacks of old suitcases filled with tiny skateboards, fake hamburgers, and other novelty items. Here was art ready to make a move.

Horn's low-budget, carny-flavored sculptural hybrids embody a charming yet emotionally crossed-wire version of plastic's afterlife. By scavenging garage sales, souvenir shops, and dollar stores, Horn disassembles, reconfigures, and breathes new life into the junk heap of youth culture. His creations are not afraid to entertain, hooking our curiosity through a seemingly endless list of synthetic byproducts, including Big Gulp cups, Flamin' Hot Cheetos bags, and merchandising from virtually every Disney and Pixar film. Horn criticizes commodification by reveling in it-proposing the idea that in commercialism's ceaseless now-time, everything is leveled and up for grabs.

On a more personal level, the show projected the chaos of a teenager's cluttered bedroom, inducing the vertiginous sensation of a high-tension video game's labyrinths, puzzles, and confrontations. Indeed, the show's often warm-and-cuddly look was belied by aspects of the sculptures featuring the nightmare corners of childhood. In Zim Zalla Zim (all works 2002), Bart Simpson's buddy Krusty the Clown is impaled on a speaker device used to take fast-food orders. Pull a string and the doll hisses insults at you, the macabre Stephen King tone setting your teeth on edge. Horn also hung clouds crafted from chicken wire and cotton batting from the ceiling; dozens of glittery white skeletons dangled among them like so many souls ascending from the earth. Most of the works served as reminders of transitory existence, getting at the childlike feelings of helplessness and grief in the face of death. (A spray-painted white four-wheeler with the remains of a crashed car thrusting outward and an Igloo "treasure chest" propped on his late father's ottoman served here as Horn's private memorials.) The entirety seemed an effort to balance conflicts between proliferation and decay; the artificial and the real; a gritty elation and the haunting childhood experiences that knock about in adult memories.

Horn is inspired by outsider art, but his work also echoes Thomas Lanigan-Schmidt's glitter-encrusted shrines and Jessica Stockholder's focus on material decision making and the poetics of seemingly displaying the mind in operation. However, Horn's art ultimately presents an earnestness and clunky literalism that reflects its own psychic universe. Some of his work is still developing, some openly flirts with sentimentality. All of it is compelling for its willful eccentricity-the mark of a young artist risking failure, a good sign.

-Susie Kalil

Planes collide in midair in Alaska but land safely

ANCHORAGE, Alaska (AP) — Two small planes collided in midair along a narrow and treacherous mountain corridor in Alaska in a crash that marked an extraordinarily rare event: No one was injured.

"It is extremely unusual," Federal Aviation Administration spokesman Mike Fergus said Monday. "It is almost unheard of."

The near-tragedy occurred Sunday afternoon as a Piper Navajo and Cessna 206 floatplane were flying directly toward each other in Lake Clark Pass — a narrow river valley that runs between Anchorage mountains.

Radar is useless in the high-traffic corridor that is just a quarter-mile wide in some places. The nine people aboard the Piper Navajo and the four in the Cessna 206 floatplane had no idea they were about to collide in the passage.

The Piper had made a round of villages and was taking passengers to Anchorage. A family doing some bear viewing was traveling in the Cessna. Visibility at the time was excellent.

"One was coming northbound. The other was going south toward Port Alsworth and they just didn't see each other until the last second," said National Transportation Safety Board investigator Larry Lewis. "Neither made any evasive maneuvers as far as we can tell."

The Cessna was slightly higher than the Piper.

"He actually hit the top of the Navajo's tail with his floats," Lewis said.

The planes sustained some minor damage but were able to land safely in Anchorage.

The FAA's Fergus described it as one of the rarest of events, a midair collision in which no one was injured and the pilots were able to safely land at airports — the Piper landed at Merrill Field, its intended destination and the Cessna went to Lake Hood.

But Lelya Alsworth described it another way: "What a miracle."

Alsworth is married to the chief pilot of Lake Clark Air, which owns the Piper.

Lewis said it can be hard to see a plane coming head-on. Wings that are 300 square feet are reduced to a 10-inch profile, he said.

"That is not much to see," he said.

Lewis said one issue that might be examined is whether pilots should make courtesy calls when traveling the pass. Such calls are made by pilots traveling near urban areas or when there are a lot of planes in the air.

The area is unregulated air space — like most of Alaska — where pilots must follow visual flight rules. Investigators will want to know whether the pilots were following the accepted practices, such as normally staying to the right side of the pass.

Lewis said the NTSB will examine the planes for damage Tuesday.

Daniel Crum was the pilot on the Piper.

The Cessna was registered to Donald Creamer Jr., according to FAA records.

Both the NTSB and the FAA are investigating.

Fergus said there is another rule that might apply when flying through the pass: "Keep your head out of the cockpit and be looking for each other."

___

Information from: Anchorage Daily News, http://www.adn.com

Commercial box spreader

Knight Manufacturing Corporation's 1170 Commercial Box Spreader features a low-friction, 3/4-inch solid HMW polyethylene floor that reduces power requirements, freeze down and is corrosion-free; a hydraulic apron drive with variable speed control; a parallel shaft-type apron gearbox; swing-out beaters to provide quick release of jams; a removable beater assembly; and shear-bolt protection. The 22-foot 1170 has a 443-cubic foot level capacity. Contact Knight Manufacturing Corporation; 1501 West 7th Avenue, P.O. Box 167, Brodhead, WI 53520; (608) 897-2131; fax (608) 8972561; kmc@knightmfg.com.

Mexico rescues 20 kidnap victims in Monterrey

MONTERREY, Mexico (AP) — A Mexican prosecution official says the army has rescued 20 people who were being held for ransom in a makeshift hut in the northern industrial city of Monterrey.

The federal official says the army discovered the hut used as a safe house after soldiers spotted a man carrying a grenade near the property.

The official said Sunday that one man was detained in the early morning rescue. The victims were found gagged and their hands and feet had been tied. They appear be from the Monterrey area and tell officials they were being held for ransoms of about $3,000 to $5,000.

The official spoke on condition of anonymity because he was not authorized to talk on the record.

PEFC Continues to Grow

In today's marketplace, certification can play a key role in the success of an organization's marketing and promotional campaigns.

When most people in the Canadian forest industry think of forest certification, the three major players that come to mind are Forest Stewardship Council (FSC), Sustainable Forestry Initiative (SFI) and Canadian Standards Association (CSA). However, there is another player in town - Programme for the Endorsement of Forest Certification (PEFC).

Recently, Canadian Forest Industries met with Paul Wooding, the director and secretary of PEFC Canada, and he quickly put to rest the common misconception that his organization competes head to head with the other certification organizations. He says PEFC at the international level, and PEFC Canada, are not forest certification programs. Their role is to endorse forest certification programs. As such, PEFC Canada represents organizations in Canada that have certified their forestry operations to the PEFCendorsed CSA Sustainable Forest Management (SFM) Standards, both the original standard first developed in 1996, and the newly endorsed CSA standard for small woodlots, as well as organizations and businesses that are certified to the PEFC International Chain of Custody Standard.

Wooding, who was a forester with Canadian Forest Products Ltd. (Canfor Corporation) for over 20 years before taking on his new role with PEFC Canada, is well versed in all of the available forest certification programs in Canada, and in particular, the CSA program, as many of Canfor's operations were, and still are, CSA certified.

As for the other major players in the certification business, Wooding says PEFC does not work with FSC, but he says they have "a friendly working relationship" with SFI, the other PEFC-endorsed organization that operates in Canada. "Products from forests certified to both the CSA and SFI program qualify for certified credits within the PEFC Chain of Custody standard," he explains, while adding that PEFC is an umbrella organization that endorses national forest certification systems developed collaboratively by all interested stakeholders and tailored to local priorities and conditions.

PEFC Background

PEFC is an international non-profit, non-governmental organization based in Geneva, Switzerland. It was founded in 1999, and today has recognized certification systems in about 30 countries, including Canada. In total, just over 220 million hectares of forestland worldwide is certified to PEFC-endorsed standards, making the organization the world's largest forest certification system.

In a report released by PEFC in April 2010, they noted that more than 75% of all certified area in North America is to PEFC standards. That's 152 million hectares in total. Of that total, 64 million hectares is certified in Canada under the CSA program while 55 million hectares in Canada is certified under the SH program. The balance of the North American total is in the U.S. - 23 million hectares that is SFI certified, and 10 million hectares that is American Tree Farm System (ATFS) certified.

According to PEFC, the CSA, SFI and ATFS certification programs they endorse all meet basic requirements, such as ensuring harvested areas are reforested, laws are obeyed and there is no unauthorized or illegal logging. Program endorsement by PEFC also ensures biological diversity is conserved, wildlife habitat is protected, soil and water resources are maintained, and timber harvesting is sustainable.

Canada first joined PEFC in 2001, with the membership held by CSA International. PEFC Canada was created and registered as a not-for-profit corporation in 2008 and it took over the membership of PEFC at that time. PEFC Canada has four directors - Wooding, Mike Alexander, who was also a forester at Canfor and worked for KPMG on forest certification prior to taking on this role, and two other forestry professionals - PEFC Canada chairman John Dunford of Vernon, B.C. -based Tolko Industries Ltd. and Guy Tremblay of Montrealbased AbitibiBowater.

Benefits for Wood lots

Wooding says one group that can realize significant benefits from PEFC certification is small woodlot owners, who in the past may have wanted certification but found the demands and requirements difficult to meet due to limited resources. In mid-July, PEFC announced they have endorsed both the Canadian Sustainable Forest Management Standard (CAN/ CSA-Z809-08) and the Canadian Sustainable Forest Management for Woodlots and Other Small Area Forests (CAN/CSA-Z804-08). He says the needs of these small woodlot owners are far different from those of the major forest licensees. Peter de Marsh, president of the Canadian Federation of Woodlot Owners, agrees.

"It is satisfying to see that it has been possible to deliver a workable standard that responds to the specific needs of Canadian woodlot owners and at the same time complies with PEFC International's sustainability benchmarks," says de Marsh, who adds that Canadian woodlots are on average less than 40 hectares in size and generally owned by rural families. "This standard gives woodlot owners across Canada, which together produce approximately 15% of the Canadian wood supply, access to the benefits of PEFC certification."

Private woodlots are the most prevalent in Atlantic Canada and in Nova Scotia alone, 53 woodlot owners have broken new ground with certification to the standard in a pilot program that was supported by the provincial government. The program, which has now grown to cover 92 woodlot owners and 107 woodlots, has received kudos from Peter Duinker, professor of resource and environmental studies at Dalhousie University in Halifax and chair of the CSA's Sustainable Forest Management Technical Committee. "This is a milestone achievement for sustainable forest management in Canada," Duinker says.

Wooding says that although they are making progress there is still work to do, as only 10% of the world's forests are certified at this time.

For more on PEFC Canada, visit: www.pefccanada.org.

Senior Albanian officials, businessman arrested on corruption charges

Two senior Albanian officials and the owner of a construction company have been arrested on accusations of corruption and abuse of office, the Interior Ministry said Thursday.

The two officials _ Spartak Gjini, 52, and Llambi Tarka, 51 _ were arrested Wednesday for allegedly granting a tender illegally to the Siret construction company by forcing other interested companies to withdraw from the competition for reconstruction of the ministry's building, the Interior Ministry said.

The owner of Siret, 39-year-old Fiqiri Pali, was also arrested, the ministry said.

The three face prison sentences of up to 10 years if convicted.

More than twenty senior officials have been arrested in the past three months on the same charges in an effort by Prime Minister Sali Berisha's government, which has been in power for two years, to fight corruption.

A recent European Union report on Albania listed corruption as a major problem that was affecting the impoverished country's efforts to join the EU and NATO.

Transparency International recently ranked Albania as being the most corrupt country in southeastern Europe, putting the nation at 105 on this year's list of 180 countries worldwide.

Monday, 12 March 2012

(null)

President Gen. Pervez Musharraf said that he expects to quit as chief of Pakistan's army by the end of November, heralding a return to civilian rule, but he rejected U.S. pressure to quickly end a state of emergency.

In an an interview with The Associated Press on Wednesday, Musharraf also rejected a demand from opposition leader Benazir Bhutto that he leave the political stage altogether.

Musharraf, wearing a dark business suit rather than his military uniform, said rising Islamic militancy required him to stay in control of the troubled nation but he left the door open for future cooperation with Bhutto if she wins January parliamentary elections.

"I take decisions in Pakistan's interest and I don't take ultimatums from anyone," Musharraf said.

The general, who seized power in a 1999 coup and sided with the United States after the Sept. 11 attacks, has appeared increasingly isolated since he declared an emergency and suspended the constitution on Nov. 3.

Authorities have rounded up thousands of opposition and human rights activists, purged the courts and blacked out independent TV news channels _ giving ammunition for his opponents to brand him a dictator.

The U.S. and other Western allies have been pushing for Musharraf to take off his uniform and end the emergency, warning it could seriously undermine the legitimacy of the elections that are meant to end eight years of direct military rule.

Washington wants Musharraf to share power with other moderate forces to try to rein in extremists allied with the Taliban and al-Qaida, who have seized control of swaths of territory near the Afghan border.

"We don't see how it is possible to have free and fair elections under emergency rule. We want to have emergency rule lifted, so that people could protest peacefully, or that they can campaign, and so that a free media can cover the election as we do here," White House press secretary Dana Perino said Wednesday, after Musharraf's comments to the AP.

Musharraf should return to democracy "as soon as possible _ we think as soon as possible is now," Perino said. "We'd like to see it done immediately."

The Commonwealth of Britain and its former colonies have threatened to suspend Pakistan unless the emergency is lifted by Nov. 22.

However, U.S. President George W. Bush continues to describe Musharraf as a trusted ally and U.S. officials have indicated they won't cut generous aid to Pakistan's military. Deputy Secretary of State John Negroponte was due in Islamabad on Friday.

"All those who are blunt enough to tell me to my face what the reality is, all of them think, yes, it will lead the country to chaos if I do not handle the political environment now with me remaining as the president," Musharraf said Wednesday.

Musharraf was in an affable mood during the 50-minute interview at his army office south of the capital, the latest in a series of meetings with foreign media designed to blunt criticism. He began by making light of unfounded rumors last week that his fellow generals had arrested him.

Musharraf had originally planned to quit as army chief by Thursday, when his presidential mandate and the term of the current Parliament expire.

But he said he was forced to delay until a court ruling on his recent re-election. He said the exact timing would depend on the reconstituted Supreme Court but expected it to happen this month.

Musharraf lashed out at Bhutto _ a political rival, but one who shares his pro-Western outlook _ for stirring up tensions since her return to Pakistan from exile was met with a suicide bombing that killed 145 people. He said there was now an "acute trust deficit" between them.

He said Bhutto was overplaying her popularity in Pakistan and thought it unlikely she could become prime minister for a third time by winning the elections, but left open the possibility of working with her if she did.

"We will see. I do function with everyone. I'm quite good at functioning with people. It depends on her if she wants to be on a confrontational course or a conciliatory one," he said.

On Tuesday, Bhutto was put under house arrest for the second time in a week to prevent her from leading a protest procession. She responded by calling on Musharraf to resign and said that despite earlier negotiations, it would be impossible for her to work under him as president.

She has been involved in a vicious war of words with conservatives in Musharraf's coalition, even accusing them of trying to kill her on her return.

She said it was likely that her party would boycott the elections _ a threat already made by other opposition parties, including that of Nawaz Sharif, whose elected government was ousted in Musharraf's 1999 coup. Together Bhutto and Sharif could form a powerful opposition bloc against the general.

Musharraf admitted he was concerned about the threat of a boycott, but said he thought it unlikely and urged opposition parties against it.

Under the emergency, Musharraf removed the chief justice of the Supreme Court and other judges who were poised to rule on whether he was eligible for a new five-year term.

Western government and opposition parties alike have serious doubts about whether elections can be free and fair under such conditions _ concerns Musharraf gave short shrift.

"Emergency is not meant to rig elections. Emergency is in fact meant to make sure that elections are held in a peaceful manner," he said.

Analysts say that lacking broad political support, Musharraf must retain the support of his Western allies and the army if he is to weather the most serious crisis of his rule.

"The emergency proclamation strengthens Musharraf's critics within the (U.S.) administration," said Craig Cohen of the Center for Strategic and International Studies in Washington.

"But enough still see him right now as having value in delivering on the war on terror, and would prefer to keep him as part of the equation" rather than turning to civilian leaders sullied by past corruption allegations or untested generals, Cohen said.

House to vote on Obama's economic stimulus plan

President Barack Obama said Wednesday he's confident that a multibillion dollar plan to kick-start the ailing economy will survive a crucial House vote.

He wasn't anxious to say how much Republican support he'll get when the roll is called, however. Democrats enjoy a sufficiently comfortable majority that they likely won't need GOP help when the vote happens later in the day. Obama had said earlier that Republican support would back up his argument that a new style of bipartisan politics is needed in Washington.

Asked whether he was confident of getting Republican support, he replied only: "I'm confident we're going to get it passed."

The president talked about prospects for the $825 billion measure during a picture-taking opportunity in the Roosevelt Room where he was surrounded by supportive CEOS from major businesses.

"These are people who make things, who hire people," Obama said. "They are on the front lines in seeing the enormous problems in our economy right now. Their ideas and their concerns have helped to shape our recovery package."

Obama said their presence underscores why it is so important to "act, and act swiftly" in getting the nation's economy going on.

His program is expansive _ and expensive. Republican support has been in doubt, and remained in doubt in the hours leading up to the vote.

House Minority Leader John Boehner wouldn't say Wednesday morning how he thought the vote would turn out. He did emphasize anew that GOP members are worried about billions in domestic spending that "has nothing to do with creating jobs or preserving jobs."

"We're for more than just cutting taxes," Boehner, R-Ohio, said on ABC's "Good Morning America."

Senate GOP leader Mitch McConnell of Kentucky told CNN that "where we have differences with the House Democrats is that the package just doesn't seem to reflect our priorities, nor the president's."

McConnell said the proportion of tax cuts versus spending increases in the version being pushed by Democrats has been "crammed down" to about 20 percent of the total instead of the 40 percent envisioned by both Republicans and Obama.

Senate committees were working on a separate version of the measure that enjoyed only slightly more support from Republicans. Congressional leaders have promised Obama they would send him the measure, which could be the single largest bill ever to go through Congress, by mid-February.

The president's first days in office have been dominated by his efforts to drum up bipartisan support for the sweeping plan to help pull the country out of the year-old recession that he inherited from former President George W. Bush. The increasingly troublesome economy _ and the federal government's response to it _ is the first major test of Obama's presidency; how he handles the volatile situation, and the effect of his stimulus package on the economy, could well set the tone for his first year in office, if not his entire term.

He is casting the measure as the first step toward turning around the moribund economy while laying the foundation for long-term objectives, like developing alternative energy sources and rebuilding the country's highways.

The House measure includes about $550 billion in spending and roughly $275 billion in tax cuts in hopes of spurring the economy and helping those directly affected. Much of the spending would be for items such as health care, jobless benefits, food stamps and other programs that benefit victims of the downturn.

As debate on the measure began Tuesday, most Democrats trumpeted it as the elixir for what ails their jobless constituents and pressed for passage; Republicans generally griped about "insane" programs that would be funded in the plan and "minuscule" tax relief for small businesses as they urged opposition.

The legislation "isn't an economic stimulus bill but a rampant spending spree," said Rep. Harold Rogers, R-Ky.

Democrats made one small change, voting to delete $20 million intended for renovating the National Mall. Republicans had criticized the expenditure as wasteful.

___

Associated Press Special Correspondent David Espo contributed to this story.

A tradition fades

Jim Leitzel learned bow hunting from his father 32 years ago. And over the years, his sons, Shane and Nicholas, learned the sport from him.

But when archery season began Sept. 30, Leitzel, 43, hunted alone in the woods near Sunbury. His sons, 21 and 20, were at work.

"My two sons hunt, but they're not dedicated to it," said Leitzel, who lives in Lewisburg and manages a Dodge dealership in Sunbury. He's also part-owner of a snowmobile dealership.

Hunters are reluctant to write an obituary for their sport, which counts more than 1 million participants in Pennsylvania. But they

recognize the pressures that endanger its future, and the future of businesses that depend on it. Those include sporting goods stores, suppliers, meat processors and motels - and farms, which rely on hunters to control the deer that damage their crops.

Since 1985, the number of hunting licenses sold annually to Pennsylvanians 16 years and younger has fallen from just under 13 1,000 to a little more than 98 000, a drop of 25 percent. Over the same period, total license sales have decreased about 11 percent.

Echoing other middle-aged hunters, Leitzel said young people are finding other things to do. As a result, they're less likely to become passionate hunters.

Hunting the estimated 1.5 million deer that roam Pennsylvania is more frustrating, as private land is increasingly posted with "no trespassing" signs. Anti-hunters make matters worse by turning people against the sport, hunters complain.

"I'm concerned, I'm very concerned, within the next two generations what will remain of hunting as we know it," said Dale Hoover, 60.

'They get bored'

Hoover learned to hunt and trap as a child, at a time when rural children had few other outlets.

In the early 1950s, Hoover tended a 7-mile loop of traps around Berrysburg, a small town in northern Dauphin County. He woke at 4:30 a.m. to check for game before school.

"More than once I was late," he recalled. But teachers were understanding. "I was reminded to be punctual, but I was never penalized."

Today, he said, young people spend their time in other ways. They watch television, play video games or participate in team sports. In the 1950s, rural teens were limited to football and baseball, but now can join soccer and track.

Hoover and a friend have tried to interest the friend's grandchildren ages 24 and 17 - in hunting. But the older men have had no luck.

"You take them hunting and don't see no deer, they get bored," said Hoover, who hopes he can teach his 3-year-old grandson to hunt when the time comes.

The financial pressures on young people are also different, said Bob Baker, the owner of Baker's Archery, Matamoras, about 17 miles north of Harrisburg. Young people today want their own cars. To pay for insurance, fuel and the like, young men work two jobs, leaving little time, or money, for hunting, which can be expensive.

Baker, 58, works 70 hours a week in his store. But he still finds time to hunt. A picture taken earlier this year shows him in northern Canada, decked out in camouflage from head to ankle and shouldering a set of Caribou antlers.

His store offers an archery class for up to 50 kids, some as young as 5. The classes, taught in February and March by Baker's only full-time employee, Jim Koppenhaver, cost $5.

"If you put a bow in a kid's hand and they try it, they're going to like it," Baker said. And, he added, bow hunting is relatively cheap. Bows cost between $100 and $650, with arrows going for as little as $15 per dozen. A hunter only needs a halfdozen to start.

But hunters know that instilling a love of their sport takes more than putting a weapon in a child's hand. Young hunters need the thrill of bagging their first buck, and that takes patience. In many areas, deer are harder to find than they used to be.

No deer, no dice

Dennis Spotts woke up around 4:20 a.m. on Sept. 30 and headed to Union County to go bow hunting with his brother Chad, Absent from the trip were Dennis' sons, Duane, 25, and Darin, 23. Dennis Spotts taught them to hunt, but they haven't joined him in 10 years.

"We tried it, and they kind of lost interest in it," said Sports, 46, a bank executive from Millersburg. "They couldn't find the game."

With deer less common on public lands,

Spotts said he's tried hunting turkeys. But it's his desire to be close to nature that keeps him coming back.

Last year, Spotts and his brother bought a camp on land in Sullivan County. The camp consists of an old mobile home, and costs about $350 a year to maintain. Spotts estimates his annual hunting expenses are around $550.

In 1996, hunters in Pennsylvania spent more than $750 million and supported more than 20,000 jobs, according to a 1998 study

by Southwick Associates, an economics consulting firm in Alexandria, Va.

For Baker, hunting has provided a modest income. But to support himself and his family, he still needed a full-time job in addition to the archery store.

Opened 31 years ago, the part-time business eventually outgrew his garage and several additions. So five years ago, he gave up other work and built a new, larger shop on Peters Mountain Road.

Antlered heads overlook Baker's main retail area, whose shelves hold a range of bow-hunting paraphernalia, from bows to boots, stocking caps to tree stands. In back, the store has an indoor shooting range, 20 yards deep, and a video-hunting system. Hunters shoot at targets on a movie screen, which records the hits.

The shop and the shooting areas are separated by a rectangular room with two tables, nine folding chairs and an RC Cola soda machine. In one comer, separated by a counter, is a small kitchen, with a fridge and coffee maker.

Animals killed by Baker and his two sons stand behind a wooden fence in the opposite comer. The display includes an eight-point buck, a pheasant, two bears and a mountain lion.

Fees from the target range and video system keep the business afloat, Baker said, declining to reveal the store's total revenue. "There's not a lot of money in it, and there's a lot of work." He also rents apartments in a building next to the store.

His archery business improved this year, but only because other stores in Pennsylvania have closed, Baker said. Baker's got busy in June, about two months earlier than normal.

But Baker is pessimistic when asked about the future. "Eventually this store won't be here," he said.

Asked why, Baker blamed "anti-hunters" who fail to understand the sport. He also blamed divorce. Kids end up with their mothers who don't introduce them to hunting, he said.

But he also recognized that young people are busy elsewhere. "That's a pretty big factor," he said, as he resumed tidying up and picking tags up off the floor.

Would Baker like his sons to take over the archery store? He paused, then said, "Honestly? I don't know."

He turned away, then turned back and smiled. "They have jobs that pay a lot more than running the store."

A close eye

To stem the decline in youth hunting, the Pennsylvania Game Commission has started programs to encourage kids participation and changed the rules to allow young people a better shot at bagging a deer. (See bottom sidebar).

The commission has also set up programs to help farmers, who lose an estimated $75 million a year due to damage caused by deer. On that count, hunters are placing their faith in Gary Alt, a respected wildlife biologist who took charge of the commission's newly created deer management section in August 1999.

"It's one of those things that we're going to have to continue to keep a close eye on," Jerry Feaser, a commission spokesman, sai d of the license numbers.

Feaser cited a less-than-expected decrease in license sales after the General Assembly raised the price in 1998, from, $12.75 to $20. It was the first increase since 1985. Feaser also said more women are hunting than ever before.

Still, the commission has established a committee to explore alternative funding methods to defer future price hikes, Feaser said. "We need to look for other ways ... to enhance the funding base for the agency."

License sales make up about half the commission ' s budget. The rest comes from federal grants, the sale of timber and coal. and from taxes on the sale of handguns. rifles and ammunition. The commission is seeking more than $68 million for 2001-2002.

But though society has changed, the commission I s purpose remains the same, Feaser said. Only the General Assembly can change it.

"We are trying to continue to promote Pennsylvania's hunting heritage," he said.

Hard work

Jim Leitzel spent Sept. 30 at the Kettle, a wooded spot 12 miles south of Sunbury and two miles downhill from the nearest road.

The hunting is great because no one goes back there and the deer are plentiful, he said.

He expressed no disappointment in his sons being elsewhere, noting he was proud to see them working. "Kids have things they'd rather be doing than freezing your ass off in the woods."

But, he added, "Hunting used to be a big part of your life."

It's still is for him.

He once spent four and a half hours dragging a buck back to his car. And three weeks into the season last year, he injured both knees climbing up a rock slide and ended up in the hospital. On Saturday, his first foray since the injury, he only saw two does and returned home empty-handed.

That didn't bother him. He enjoys being' outdoors and sometimes just watches the deer linger beneath his tree stand.

"I've killed plenty," he said.

Report: Groom kills 3 guest in accidental shooting

The state-run news agency says a groom has killed his father and two aunts after opening fire into the air with an automatic weapon to celebrate his wedding.

The Anatolia news agency says eight other relatives were injured during Sunday's celebration in the southeastern province of Gaziantep.

It says the groom lost control of the weapon and accidentally aimed at guests. He was arrested.

It is tradition in Turkey to shoot into the air to celebrate weddings, circumcisions or sports victories. Turkey has failed to curb the practice despite imposing harsher punishments to cut down on stray bullet accidents.

Police in Gaziantep were not available for comment.

Actor Morgan Freeman injured in car accident

Oscar-winning actor Morgan Freeman has been injured in car accident in Mississippi and is in a hospital in Memphis, Tennessee.

Regional Medical Center spokeswoman Kathy Stringer says Freeman is in serious condition.

The hospital, commonly known as The Med, is an acute-care teaching facility that serves patients within 150 miles (240 kilometers) of Memphis.

Ashley Norris, manager of the Ground Zero Blues Club in Clarksdale that is owned by Freeman, confirmed the actor was in a wreck. Norris said she had no other details.

The accident apparently occurred in Tallahatchie County Mississippi, but the sheriff's department referred calls to the Mississippi Highway Patrol. A highway patrol spokesman wasn't immediately available for comment.

Cavs finally prevail in prime time

Rookie LeBron James had 23 points and nine assists, and CarlosBoozer scored a career-high 28 as the Cleveland Cavaliers finally wonon national TV, 95-86 over the visiting Detroit Pistons on Thursday.

James, whose addition to the Cavs has given them unprecedentedexposure and pressure, helped Cleveland improve to 1-5 in prime-timetelecasts. The Cavs have won just two of their last 11.

Cleveland also snapped an eight-game losing streak to Detroit. TheCavs hadn't beaten the Pistons since Dec. 4, 2001.

The win also was Cleveland's first over a team with a winningrecord since the Cavs defeated New Orleans on April 5.

Ricky Davis, whose name continually pops up in trade rumors, had15 points, nine rebounds and five assists. Davis also had a viciousdunk, cutting through four Pistons in the fourth quarter to throw onedown as the Cavs were putting it away.

HORNETS 111, SUNS 101: Baron Davis scored 14 of his 29 points inthe fourth quarter, and visiting New Orleans spoiled the debut ofPhoenix coach Mike D'Antoni.

Six Hornets scored in double figures, including all five starters,and New Orleans outrebounded Phoenix 40-25, 12-3 on the offensiveboards.

David Wesley scored 14 points, George Lynch and P.J. Brown added13 apiece, and Jamaal Magloire had 11 points and 14 rebounds.

The Suns have lost four in a row and seven of eight to fall intolast place in the Western Conference for the first time since the1996-97 season.

SPURS 71, ROCKETS 67: Tim Duncan scored 14 of his 22 points in thesecond half to lead visiting San Antonio past Houston in a game inwhich the teams combined for the lowest-scoring first half in NBAhistory.

Duncan scored seven of his 10 fourth-quarter points in a 15-6 runas the Spurs rallied from a four-point deficit. Devin Brown made twofree throws to seal San Antonio's fifth straight win.

The teams struggled with their shooting in the first half andcombined for an NBA-record low 55 points, the fewest two-team totalsince the shot clock was introduced in the 1954-55 season.

AP

Wednesday, 7 March 2012

Students homor alumnus for work in human resource field

This fall, while speaking to the Baylor Association for Human Resource Management (BAHR), David Rodgers was caught by surprise when students presented him with a plaque and gift certificate in appreciation for his personal commitment to students and consistent support of Baylor and the association.

"David is our good luck charm," says BAHR adviser Dr. Joe Cox. "That's why for the past 15 years we have started off the year with him. After all, David was the first president of the chapter-known in 1979-80 as the Baylor David was the first president of Baylor Personnel Association."

Rodgers is …

Sherrod not sure she'd return to Ag Department

The woman at the center of a racially tinged firestorm involving the Obama administration and the NAACP says she's not certain whether she would return to the Agriculture Department if invited back.

Shirley Sherrod says she's perplexed by the uproar over remarks she made 24 years ago about giving shortshrift attention to pleas for assistance by a white farmer. Sherrod, who is black, says …

Monday, 5 March 2012

Grow Ca[F.sub.2] crystals in high yields. (Chementator).

At a fluorine laser's 157-nm wavelength, current optical materials such as fused silica transmit light so poorly that they can no longer pattern circuits onto silicon wafers. Calcium fluoride is the leading candidate for new lens materials, but today's crystal-growing technology relies on the Bridgman-Stockbarger method, which depends on good heat conduction within the growing crystal. As Ca[F.sub.2] is an insulator, however, this existing method proves time-consuming and costly, with yields limited to only 1-3%.

Work at Single Crystal Technologies, LLC (SCT; Gilbert, Ariz.; sct-llc.com), however, promises to free the semiconductor industry from a potential …

Site-directed mutagenesis studies to probe the role of specific residues in the external loop (L3) of OmpF and OmpC porins in susceptibility of Serratia marcescens to antibiotics.(Report)

Abstract: Serratia marcescens is a nosocomial bacterium with natural resistance to a broad spectrum of antibiotics, making treatment challenging. One factor contributing to this natural antibiotic resistance is reduced outer membrane permeability, controlled in part by OmpF and OmpC porin proteins. To investigate the direct role of these porins in the diffusion of antibiotics across the outer membrane, we have created an ompF-ompC porin-deficient strain of S. marcescens. A considerable similarity between the S. marcescens porins and those from other members of Enterobacteriaceae was detected by sequence alignment, with the exception of a change in a conserved region of the third external loop (L3) of the S. marcescens OmpC protein. Serratia marcescens OmpC has aspartic acid instead of glycine in position 112, methionine instead of aspartic acid in position 114, and glutamine in position 124, while in S. marcescens OmpF this is a glycine at position 124. To investigate the role of amino acid positions 112, 114, and 124 and how the observed changes within OmpC porin may play a part in pore permeability, 2 OmpC sites were altered in the Enterobacteriaceae consensus (D112G and M114D) through site-directed mutagenesis. Also, Q124G in OmpC, G124Q in OmpF, and double mutants of these amino acid residues were constructed. Antibiotic accumulation assays and minimal inhibitory concentrations of the strains harboring the mutated porins were performed, while liposome swelling experiments were performed on purified porins. Our results demonstrate that the amino acid at position 114 is not responsible for either antibiotic size or ionic selection, the amino acid at position 112 is responsible for size selection only, and position 124 is involved in both size and ionic selection.

Key words: Serratia marcescens, antibiotic resistance, porins, site-directed mutagenesis.

Resume: Serratia marcescens est une bacterie nosocomiale possedant une resistance naturelle a un large spectre d'antibiotiques, rendant son traitement difficile. La permeabilite reduite de la membrane externe, controlee par les porines OmpF et OmpC, est un facteur qui contribue a cette resistance naturelle aux antibiotiques. Afin d'examiner le role direct de ces porines dans la diffusion des antibiotiques a travers la membrane externe, nous avons cree une souche de S. marcescens deficiente en ompF-ompC. Une similarite considerable a ete trouvee entre les porines de S. marcescens et celles d'autres membres des Enterobacteriaceae par un alignement de sequences, a l'exception d'un changement au sein d'une region conservee de la troisieme boucle externe (L3) de la proteine OmpC de S. marcescens. OmpC de S. marcescens possede un acide aspartique plutot qu'une glycine en position 112, une methionine plutot qu'un acide aspartique en position 114 et une glutamine en position 124, alors que dans OmpF de S. marcescens, ce residu est une glycine. Afin de determiner le role des acides amines situes en position 112, 114 et 124, et determiner comment les changements observes au sein de la porine OmpC peuvent contribuer a la permeabilite du pore, deux sites chez OmpC ont ete modifies a l'interieur de la sequence consensus des Enterobacteriaceae (D112G et M114D) par mutagenese dirigee. De meme, Q124G de OmpC et G124Q de OmpF, ainsi que des doubles mutants ont ete construits. Des essais d'accumulation d'antibiotiques et les concentrations minimale inhibitrice des souches exprimant ces porines mutees ont ete effectues, alors que des experiences de gonflement de liposomes ont ete realisees avec les porines purifiees. Nos resultats demontrent que l'acide amine situe en position 114 n'est ni responsable de la selection selon la taille de l'antibiotique ni de la selection ionique, l'acide amine situe en position 112 est responsable de la selection selon la taille alors que l'acide amine situe en position 124 est implique dans les deux types de selection, selon la taille et ionique.

Mots-cles: Serratia marcescens, resistance aux antibiotiques, porines, mutagenese dirigee.

[Traduit par la Redaction]

Introduction

Serratia marcescens is a Gram-negative enteric bacterium, which has become an important opportunistic pathogen associated with a number of life-threatening diseases and nosocomial infections, such as urinary tract infections, respiratory tract infections, meningitis, septicaemia, and wound infections (Hejazi and Falkiner 1997). This organism possesses a high intrinsic resistance to a variety of antibiotics including aminoglycosides, [beta]-lactams, first- and second-generation cephalosporins, and quinolones (Fujimaki et al. 1989; Kumar and Worobec 2003) making treatment very difficult. The basis of this antibiotic resistance is multi-factorial, involving different mechanisms for each group of antibiotics. For example, resistance to [beta]-lactam antibiotics is achieved by (i) outer membrane impermeability mediated by porins (Gutmann et al. 1984), (ii) [beta]-lactamases found in the periplasm that degrade these drugs (Sanders and Sanders 1992), and (iii) altered inner membrane penicillin-binding proteins, which are the target for these antibiotics (Gunkel et al. 1991). Likewise, resistance to quinolones can be a result of mutations in DNA gyrase (the target enzyme for this group of antibiotics) (Fujimaki et al. 1989) and (or) over-expression of multidrug resistance efflux pumps (Ma et al. 1994).

The multifactorial nature of antibiotic resistance was demonstrated in a study using Enterobacter aerogenes, a related nosocomial pathogen. Investigators reported a simultaneous change in membrane permeability because of porin deficiency concomitant with the expression of an efflux mechanism, which renders this bacterium resistant to both [beta]-lactam and fluoroquinolone antibiotics (Mallea et al. 1998). One of our objectives was to study the role of outer membrane permeability in the [beta]-lactam resistance of S. marcescens.

For [beta]-lactam antibiotics to be effective in Gram-negative bacteria they must penetrate the outer membrane. The Gram-negative outer membrane is a semipermeable lipid bilayer that behaves like a molecular sieve to allow the passage of small hydrophilic molecules, such as nutrients, waste products, and [beta]-lactam antibiotics (Nikaido 1994), into and out of the cell. The degree of permeability of this membrane depends on the presence of poreforming porin proteins, which are membrane-spanning molecules that form water-filled channels (Nikaido 1994). Channel size and hydrophilicity are determined by an eyelet loop of the polypeptide chain that extends into the pore (Nikaido 1994). Nonspecific porins are typically involved in the passage of [beta]-lactam and other families of antibiotics (e.g., Escherichia coli OmpF/C (Nakae 1976; Mizuno et al. 1983) or OprF of Pseudomonas aeruginosa (Woodruff and Hancock 1989)).

Two major nonspecific porins, OmpF and OmpC, have been identified in S. marcescens (Hutsul and Worobec 1994, 1997). Although the role of OmpF and OmpC in the antibiotic resistance of E. coli (Mortimer and Piddock 1993) and other members of Enterobacteriaceae, such as E. aerogenes and Klebsiella pneumoniae, has been studied extensively (Gutmann et al. 1984), little is known about S. marcescens porins. Changes in porin copy number, size, selectivity, or function can alter the …

ALBANY POLICE CHARGE 7 PEOPLE IN 2 SEPARATE MUGGINGS.(CAPITAL REGION)

Byline: CAROL DEMARE Staff writer

ALBANY City police have arrested suspects in two recent muggings one in which four youths stole chewing gum from another teen, and the other in which three young men stole an elderly woman's handbag.

In the first case, four 15-year-olds forcibly stole a piece of gum from a 14-year-old Albany High School student on Sept. 6 at about 3 p.m. in the 300 block of Western Avenue after knocking him to the ground.

Arrested and charged as adults with second-degree robbery were Albany residents Clarence Edmonds of 75 Third Ave., Jermaine Cox of 41 Osborne St., Brandon Inman of 279 Northern Blvd., and Lewis Kornegay of …

Virus spurred high blood pressure _ in mice

Provocative new research suggests that a common virus might play a role in high blood pressure.

The work, by Harvard University scientists, so far is only in mice _ and the usually symptomless infection is so widespread that proving an effect in people will be tough.

Still, it's the latest clue that infections may somehow affect a number of the factors that lead to heart disease, from stiffening arteries to obesity.

"There's likely to be considerable skepticism about this in the medical profession," acknowledged lead researcher Dr. Clyde Crumpacker, an infectious disease specialist at Beth Israel Deaconess Medical Center in Boston. But, …

Service-Oriented Architecture

4What is it? Service-Oriented Architecture (SOA) is an approach to software or systems architecture built around services - computing components that can be flexibly reused and recombined.

In an SOA, software components advertise themselves on the corporate network as offering a service that other applications can discover and use. An order management system might advertise a lookup service that would be useful to both a customer service application and a profitability analysis app, for example. The contrast is with point-to-point integration approaches, in which separate software interfaces would have to be developed between the two applications seeking data from the orders …

Sunday, 4 March 2012

BILL BONANZA.(regulations on low-power television stations)(Sen. Conrad Burns (R-Mont.))(Brief Article)

Ten low-power television stations, most owned by the same company, would be permitted to offer two-way wireless Internet services under a pilot program approved by the Senate Commerce Committee Last week.

The plan allows 10 specified LPTV stations to offer two-way services as Long as there is no interference with existing full-power stations. Sen. Conrad Burns (R-Mont.), the bill's sponsor, said the new service is …

Studies from Y. Kim et al have provided new data on drug delivery.

According to a study from Seoul, South Korea, "Surface modification of amine-terminated polyamidoamine (PAMAM) dendrimers by poly(ethylene glycol) (PEG) groups generally enhances water-solubility and biocompatibility for drug delivery applications. In order to provide guidelines for designing appropriate dendritic scaffolds, a series of G3 PAMAM-PEG dendrimer conjugates was synthesized by varying the number of PEG attachments and chain length (shorter PEG(550) and PEG(750) and longer PEG(2000))."

"Each conjugate was purified by size exclusion chromatography (SEC) and the molecular weight (MW) was determined by H-1 NMR integration and matrix-assisted laser desorption …

PBM offer raises concerns about market control; Express Scripts bid trumps CVS offer for Caremark Rx.(News)

Byline: GLORIA GONZALEZ

While the possible merger of two of the nation's largest pharmacy benefit managers has potential advantages for employers, some express concern that ongoing consolidation of the PBM industry will lead to decreased competition and, ultimately, higher prescription drug benefit costs.

St. Louis-based Express Scripts Inc. has proposed a $26 billion acquisition of its larger rival Caremark Rx Inc. in a deal that would create the largest PBM in lives covered and revenues (see box). The Express Scripts offer, if accepted, would derail Nashville, Tenn.-based Caremark's planned $21 billion merger with Woonsocket, R.I.-based CVS Corp. (BI, Nov. 6).

The PBM industry has already seen significant consolidation in recent years, with Caremark purchasing rival AdvancePCS in 2003 (BI, Sept. 22, 2003) and Express Scripts completing five acquisitions since 1998. The three largest PBMs-Franklin Lakes, N.J.-based Medco Health Solutions Inc., Caremark and Express Scripts-control 70% to 75% of the U.S. PBM market.

While the merger of CVS and Caremark was generally seen as creating significant benefits for …

Rowdy revelers surrounding cars after Lakers win

Rowdy revelers are surrounding cars that are attempting to leave Staples Center and random fights and bonfires are breaking out near the arena.

Television news footage showed several people jumping on a taxi Thursday night as it attempted to leave the area near the area after the Los Angeles Lakers win over the Boston Celtics. Someone opened a rear door of the vehicle while others rocked it back and forth. The taxi eventually made its way through the crowd and out of the area.

KCAL-TV helicopter footage showed a man being beaten by several people on Flower Street north of Olympic Boulevard.

The Los Angeles Fire Department says several people were …

Light plane crashes at Israeli airport, 4 die

JERUSALEM (AP) — Israeli rescue services say a small plane has crashed at the airport in the city of Haifa, killing all four people on board.

The rescue services say the light civilian aircraft crashed on Thursday morning …

Two Perm Airlines aircraft issue false hijacking alarms.

AIRLINE INDUSTRY INFORMATION-(C)1997-2002 M2 COMMUNICATIONS LTD

Two aircraft, operated by Russian carrier Perm Airlines, sent hijacking alarms in error yesterday (28 October).

The two An-24 turboprop aircraft were both travelling from Moscow to the Siberian city of Perm when the hijacking alarms …

NAPSTER INC. FACES MUSIC ABOUT POSSIBLE SALE.(Business)

Napster Inc., the Internet music pioneer facing a challenge from dissident shareholders, said it is willing to consider a sale and is working with UBS Investment Bank as an adviser.

The board, fighting off investors seeking three board seats and a sale of the company, will evaluate all options to increase the stock price, the Los …

Saturday, 3 March 2012

EMPIRE SHOULD REMAIN NOT-FOR-PROFIT GROUP.(MAIN)

Byline: EILEEN BAUL Rosendale

As Dr. Stocker, president of Empire Blue Cross and Blue Shield, supports a conversion from not-for-profit to for-profit, I ask him these questions:

Will all executives get big raises and bonuses, and allow doctors to buy and profit on Empire stock, leaving less money to pay into medical bills, resulting in …

Fatigue is common complaint of patients with cancer.

2003 OCT 9 - (NewsRx.com & NewsRx.net) -- A new review finds clinicians rarely discuss fatigue with their patients, even though it has a significant impact on quality of life and effective treatments are available.

The literature review of cancer-related fatigue (CRF) will be published in the November 1, 2003, issue of Cancer and is the most up-to-date summary of current knowledge about CRF and its management and the areas of potential research. It is currently available online (www.interscience.wiley.com/cancer).

Until recently, fatigue has gone largely ignored by clinicians who were tackling more glaring and acute symptoms such as nausea and vomiting. The …

Pullman monument will be removed at week's end

The City of Chicago and the administration of the A. Philip Randolph Pullman Porter Museum have agreed to move a 10-foot monument dedicated to Randolph onto museum property Friday.

But not everyone is happy about it.

Lyn Hughes, founder of the museum, said the board was notified in September that the monument - installed 10 years ago - was on city-owned property and would have to be removed by Sept. 29. They were given a 90-day stay until Dec. 29.

"On that day, the city sent a letter to our lawyer saying that we were to type the information on our letterhead and fax it back to the city that day," Hughes said. "The museum board president had to sign it. It was signed …

My BE.(All Access)(blackenterprise.com/ipad)(Website overview)(Brief article)

Now that you've downloaded the BE app to your shiny iPad, enjoyed a few issues, and book marked your favorite articles, you must give our MyBE feature a spin! MyBE helps ensure you're always on track by gathering all …

AILING TIBETAN PRISONER RELEASED.(CAPITAL REGION)

Byline: TED ANTHONY Associated Press

BEIJING -- A Tibetan teacher believed to be China's longest-held political prisoner arrived in the United States on Saturday, freed nine years early on medical grounds, a leading U.S. human rights activist said.

Tanak Jigme Sangpo, 74, arrived in Chicago from Beijing on Saturday afternoon in ``pretty good health'' despite serious high blood pressure and coronary disease, said John Kamm, president of the San Francisco-based Duihua Foundation. He said Jigme Sangpo was ``frail but mentally sharp.''

Kamm attributed the release to China's post-Sept. 11 desire to bolster relations with Washington.

``I'm not …